The Industrial Internet-of-Things Innovation (I³) programme is a new industry-driven initiative by the Science and Engineering Research Council (SERC) of A*STAR. The I³ programme is a public-private-partnership established by A*STAR as part of the Future of Manufacturing Initiative to develop and accelerate the adoption of IoT technologies. To complement existing A*STAR Model Factories, I³ focuses on developing smart integrated asset and product deployment solutions for real industry applications that extend beyond the factory floor. The I³ programme operates as an industry-driven consortium by bringing together end users, solution providers and research performers to collaborate and translate existing technologies into end-to-end IIoT solutions, as well as co-develop new technologies with A*STAR Research Institutes (RIs) and Institutes of Higher Learning (IHLs) in Singapore. SMEs and startups can also benefit from this open collaboration as they upgrade their capabilities and position themselves as solution providers to the end users in the consortium.